Mahardika, Dimas Pradhasumitra and Yusrita, Eli and Surya, Alfin and Juariah, Siti (2021) Phytogenic silver nanoparticle (AgNP) from Ananas comosus (L) Merr. peel extract to inhibiting the pathogen resistance. iop science, 1811 (1). 012124.

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Abstract

Green Nanotechnology utilizing various plant extracts (phytogenic) has widely known and proven as ecofriendly and inexpensive scientific approach with numerous potentials in medical treatments. Silver nanoparticles (AgNPs) has been commonly used in home cleaning products, wound dressing and antimicrobial coating for medical equipment. Furthermore, Ananas comosus (L.) Merr. (AC) is an exotic tropical fruit, found abundantly in Riau Province. It is rich on bromelain enzyme in addition to its potential as antibacterial, antioxidant as well as anticancer. Contrarily, utilization of waste from plants, fruits and food as alternative natural reduction and capping agents from metal ion nanoparticles is still being developed. Combining these two elements has an immense potential as an effective alternative therapeutic substance in the near future. The purpose of this research is to analyze AgNPs from AC by characterizing the product of biosynthesis. Furthermore, this research will also observe antimicrobial activity of AC-AgNPs against Methicillin Resistant Staphylococcus aureus (MRSA). As a result, the biosynthesis produced AC-AgNPs which showed the ability to inhibit the growth of MRSA with an average of 10.59 mm, 20% more effective compared to pure AC extract. AC-AgNPs formation were characterized using UV–visible spectroscopy in the interval of 439– 486 nm.

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